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  • 4'-Trifluoromethyl-2-biphenyl carboxylic acid
4'-Trifluoromethyl-2-biphenyl carboxylic acid的可视化放大

4'-Trifluoromethyl-2-biphenyl carboxylic acid

4'-Trifluoromethyl-2-biphenyl carboxylic acid 是一种具有口服活性的降血脂剂。

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  • 货号: ajcf17168
  • CAS: 84392-17-6
  • 别名:
  • 分子式: C14H9F3O2
  • 分子量: 266.22
  • 纯度: >98%
  • 溶解度: DMSO : ≥ 250 mg/mL (939.07 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent[1].


4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys[1].

Animal Model: Diet-induced hypercholesterolemic African green monkeys[5]
Dosage: 15-60 mg/kg
Administration: Oral administration (p.o.)
Result: Reduced serum LDL-cholesterol concentrations.


[1]. Lewis MC, et al. Evaluation of the hypolipidemic activity of xenalipin in experimental animals. Atherosclerosis. 1987 Mar;64(1):27-35.

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