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EPI-589 是一种醌衍生物,是一种安全且耐受性良好的氧化还原酶 (oxidoreductaseenzyme) 抑制剂。EPI-589 可用于肌萎缩性侧索硬化症 (ALS) 的相关研究。
IC50: oxidoreductase enzyme[1]
EPI-589, a quinone derivative, is a safe and well tolerated oxidoreductase?enzyme inhibitor. EPI-589 has the potential for the treatment of amyotrophic lateral sclerosis (ALS)[1].
EPI-589 exhibits a significant improvement in cerebrospinal fluid (CSF) and plasma-based biomarkers known to be associated with neuroinflammation and ALS disease progression[2].
[1]. BioElectron's EPI-589 Shows Positive Results in ALS Patients in Phase 2a Trial
[2]. Phase IIa trial of EPI-589 in ALS shows improvement in CSF
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