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Propofol-d17 β-D-glucuronide 是 Propofol β-D-glucuronide 的氘代物。
Propofol-d17 β-D-glucuronide is the deuterium labeled Propofol β-D-glucuronide[1].
Stable heavy isotopes of drogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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