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  • 33-BCRP Inhibitor
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33-BCRP Inhibitor

一种BCRP抑制剂

原价
¥675-5387
价格
540-4310
33-BCRP Inhibitor的二维码

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  • 库存: 现货
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  • 货号: ajcf23552
  • CAS:
  • 别名: 33-Breast Cancer Resistance Protein Inhibitor
  • 分子式: C19H13N7
  • 分子量: 339.4
  • 纯度: >98%
  • 溶解度: DMSO: Soluble,Methanol: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

33-BCRP inhibitor is an inhibitor of breast cancer resistance protein (BCRP).1 It sensitizes mitoxantrone-resistant H460/MX20 lung cancer cells to mitoxantrone-induced cell death alone and in combination with UV radiation. 33-BCRP inhibitor also sensitizes KB-C2 epidermal carcinoma cells overexpressing P-glycoprotein (P-gp), also known as multidrug resistance protein (MDR), to colchicine-induced cell death. It increases intracellular accumulation of mitoxantrone in H460/MX20 cells when used at a concentration of 5 μM.

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