Background
Kresoxim-metl-d7 is intended for use as an internal standard for the quantification of kresoxim-metl by GC- or LC-MS. Kresoxim-metl is a strobilurin fungicide.1 It inhibits conidial germination of V. inaequalis isolates from apple orchards (EC50s = 0.00033-0.0078 mg/L). Kresoxim-metl also inhibits mycelial growth (EC50 = 0.240 mg/L) and is fungicidal against Saprolegnia (MIC = 1 mg/L).2 It increases intracellular calcium levels and disrupts the mitochondrial membrane potential in mouse cortical cultures in a concentration-dependent manner.3 Kresoxim-metl is toxic to goldfish (C. auratus; LC50 = 0.807 mg/L).2 Formulations containing kresoxim-metl have been used in the control of fungi in agriculture.
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