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  • Mitraciliatine
Mitraciliatine的可视化放大

Mitraciliatine

一种生物碱，是μ-阿片受体的部分激动剂和κ-阿片受体的激动剂。

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￥4987-8487
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￥ 3990-6790
Mitraciliatine的二维码

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  • 库存: 现货
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  • 货号: ajcf23696
  • CAS: 14509-92-3
  • 别名:
  • 分子式: C23H30N2O4
  • 分子量: 398.5
  • 纯度: >98%
  • 溶解度: Methanol: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Mitraciliatine is an alkaloid that has been found in M. speciosa (Kratom in Thai) and is a μ-opioid receptor (MOR) partial agonist and κ-opioid receptor (KOR) agonist.1,2 It is selective for MOR and KOR over the δ-opioid receptor (DOR; EC50s = 228, 218, and >1,000 nM, respectively, for the mouse receptors in a GTPγS binding assay).2 Mitraciliatine (100 nmol/animal, i.c.v.) increases the latency to withdrawal in the warm water tail withdrawal assay in mice, an effect that can be reversed by knockout of MOR but not KOR. Unlike morphine, mitraciliatine does not induce perlocomotion or respiratory depression.

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