S-Geranylgeranyl-L-glutathione

一种P2RY8配体

原价

￥437-3050

价格

￥ 350-2440

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产品引用

Cell.Cell host & microbe.November 8, 2023
Cell . MOLECULAR PLANT . 1 February 2023
Cell . Immunity . August 10, 2021
Nature Communications.1413 (2022)
ACS . Nano Lett . April 10, 2023

S-Geranylgeranyl-L-glutathione详情
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Background

S-Geranylgeranyl-L-glutathione is a ligand of the orphan G protein-coupled receptor (GPCR) P2RY8.¹ It selectively induces internalization of P2RY8 over sphingosine-1-phosphate receptor 2 (S1P₂), GPR55, cysteinyl leukotriene receptor 1 (CysLT₁ receptor), and CysLT₂ receptor at 100 nM. S-Geranylgeranyl-L-glutathione (10 nM) inhibits the migration of P2RY8-expressing WEHI-231 B cell lymphoma cells and isolated human tonsil germinal center B cells induced by chemokine (C-X-C motif) ligand 12 (WEHI-231).

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信号通路

生命科学

有机化学

无机化学

材料科学

S-Geranylgeranyl-L-glutathione

S-Geranylgeranyl-L-glutathione详情

Background