Myelopeptide-2 (MP-2)
用于恢复人T淋巴细胞的肽
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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1mg￥375.00300.00- +
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5mg￥1100.00880.00- +
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10mg￥1912.001530.00- +
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25mg￥2537.002030.00- +
- 货号: ajcp4572
- CAS: N/A
- 别名: H2N-Leu-Val-Val-Tyr-Pro-Trp-OH
- 分子式: C41H57N7O8
- 分子量: 775.93
- 纯度: ＞98%
- 溶解度: ≥77.5mg/mL in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Myelopeptide-2 (MP-2) (C41H57N7O8), with the sequence Leu-Val-Val-Tyr-Pro-Trp, is originally isolated from the supernatant of porcine bone marrow cell culture, and is able to restore the mitogen responsiveness of human T lymphocytes inhibited by conditioned medium from HL-60 leukemia cells or measles virus. The MP-2 recovery effect is connected with its influence on the CD3 and CD4 antigen expression on T lymphocytes. Research results also suggest that the MP-2 involvement in regulatory processes is directed to the maintenance of immune homeostasis. This peptide is perspective to be applied in antitumor and antivirus therapy.
参考文献:
1. Mikhailova AA, Belevskaya RG, Kalyuzhnaya M, Fonina LA, Liashenko VA, Petrov RV. Myelopeptide-2 recovers interleukin-2 synthesis and interleukin-2 receptor expression in human T lymphocytes depressed by tumor products or measles virus.
