Angiotensin 1/2 (1-7) amide
Vasoconstrictor
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包装价格促销价数量
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1mg￥375.00300.00- +
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5mg￥1100.00880.00- +
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10mg￥1912.001530.00- +
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25mg￥2525.002020.00- +
- 货号: ajcp4600
- CAS: N/A
- 别名: H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide
- 分子式: C41H63N13O10
- 分子量: 898.02
- 纯度: ＞98%
- 溶解度: ≥89.8mg/mL in DMSO
- 储存: Store at -20°C
- 库存: 现货
Background
Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse.
Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe | His-Leu) is an octapeptide that is converted from Angiotensin I (AI) through the removal of two C-terminal residues by angiotensin-converting enzyme (ACE), primarily by ACE within the lung (but also those present in endothelial and kidney epithelial cells). Ang-(1–7) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively. [1]
Angiotensin I/II (1-7) amide is an amide derivative of angiotensin II that is a powerful vasoconstrictor and vasopressor, and is used in the treatment of certain hypotensive states. Angiotensin I/II (1-7) amide is usually administered by slow intravenous infusion, and sometimes intramuscularly or subcutaneously.
参考文献:
1. Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45.
