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  • VSV-G Peptide
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VSV-G Peptide

肽序列-YTDIEMNRLGK

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VSV-G Peptide的二维码
  • 库存: 现货
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  • 货号: ajcp4720
  • CAS: N/A
  • 别名: H-Tyr-Thr-Asp-Ile-Glu-Met-Asn-Arg-Leu-Gly-Lys-OH
  • 分子式: C57H94N16O19S
  • 分子量: 1339.52
  • 纯度: >98%
  • 溶解度: >134mg/mL in DMSO
  • 储存: Desiccate at -20°C
  • 库存: 现货

Background

VSV-G , a vesicular stomatitis virus G (VSV-G) protein fragment. VSV-G protein is commonly used in biomedical research to pseudotype retroviral and lentiviral vectors, conveying the ability to transduce a broad range of mammalian cell types with genes of interest. [1] The VSIV G protein has also been used in cytological studies of trafficking in the endomembrane system. Immunoelectron microscopy suggests that VSIV G protein moves from cis to trans Golgi bodies without being transported between them in vesicles, supporting the cisternal maturation model of Golgi trafficking. [2]

参考文献:
1. Cronin J, Zhang XY, Reiser J (2005). "Altering the tropism of lentiviral vectors through pseudotyping". Curr Gene Ther 5 (4): 387–98.
2. Mironov AA, Beznoussenko GV, Nicoziani P, Martella O, Trucco A, Kweon H, Giandomenico DD, Polishchuk RS, Fusella A, Lupetti P, Berger EG, Geerts WJC, Koster AJ, Burger KNJ, Luini A (2001). "Small cargo proteins and large aggregates can traverse the Golgi by a common mechanism without leaving the lumen of cisternae". JCB 155 (7): 1225–38.

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