PG-11047 tetrahydrochloride
PG-11047 tetrahydrochloride（CGC-11047）是一种多胺类似物，是天然多胺精胺的无功能竞争对手。
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包装价格促销价数量
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1mg￥1450.001160.00- +
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5mg￥4237.003390.00- +
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- 货号: ajcf32402
- CAS: 206991-64-2
- 别名: CGC-11047 tetrahydrochloride
- 分子式: C14H36Cl4N4
- 分子量: 402.27
- 纯度: ＞98%
- 溶解度: H<sub>2</sub>O : ≥30 mg/mL (74.58 mM)
- 储存: -20°C
- 库存: 现货
Background
PG-11047 (CGC-11047), a polyamine analogue, is a nonfunctional competitor of the natural polyamine spermine. PG-11047 has broad spectrum anticancer activities.
参考文献:
[1]. Wen-Lin Kuo, et al. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009 Dec 14;7:77.
[2]. Murray Stewart T, et al. A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma. Cancer Chemother Pharmacol. 2021 Jan;87(1):135-144.
