Benzophenone-d10 是 Benzophenone 的氘代物。Benzophenone 是一种内源性代谢产物。
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Benzophenone-d10 is the deuterium labeled Benzophenone. Benzophenone is an endogenous metabolite.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
参考文献:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.