TP0628103 TFA
TP0628103 (Compound 18) TFA 是MMP-7 的选择性抑制剂，IC50值为 0.17 nM，在癌症和纤维化中发挥重要作用。
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包装价格促销价数量
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5mg￥2387.001910.00- +
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10mg￥3687.002950.00- +
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- 货号: ajcf41022
- CAS: 2865106-78-9
- 别名:
- 分子式: C53H68ClF6N11O13S
- 分子量: 1248.68
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
TP0628103 (Compound 18) TFA is a selective inhibitor ofMMP-7, with theIC50value of 0.17 nM that plays an important role incancerand fibrosis[1].
参考文献:
[1].Yusuke Oka, et al. Discovery of TP0628103: A Highly Potent and Selective MMP-7 Inhibitor with Reduced OATP-Mediated Clearance Designed by Shifting Isoelectric Points. J Med Chem. 2024 Jan 12. doi: 10.1021/acs.jmedchem.3c01967.
