NHE-1-IN-2
NHE-1-IN-2 (compound 7g) 是一种有效的NHE-1抑制剂，其IC50为 0.78 μM。
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包装价格促销价数量
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5mg￥2825.002260.00- +
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10mg￥4375.003500.00- +
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- 货号: ajcf41038
- CAS: N/A
- 别名:
- 分子式: C23H20ClN3O3
- 分子量: 421.88
- 纯度: ＞98%
- 溶解度: DMSO: 87.5 mg/mL(207.40 mM; Need ultrasonic)
- 储存: Store at -20°C
- 库存: 现货
Background
NHE-1-IN-2 (compound 7g) is a potentNHE-1inhibitor with anIC50of 0.78 μM. NHE-1-IN-2 alleviates left ventricular systolic dysfunction in mice model of heart failure[1].
参考文献:
[1].Cao M, et al. Novel sodium-hydrogen exchanger 1 inhibitors with diphenyl ketone scaffold: Design, Synthesis, mechanism and evaluation in mice model of heart failure. Eur J Med Chem. 2025 Jul 5;291:117585.
