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Arylquin 1
A Par-4 secretagogue
Apoptosis Inhibitor
A cell-permeable inhibitor of caspase-3 activation
AEG 3482
An inhibitor of p75NTR- and NRAGE-induced apoptosis
Cladribine
A nucleoside analog and prodrug form of 2-CdATP
Destruxin B
An insecticidal mycotoxin
ONC201
A TRAIL-inducing compound
Epibrassinolide
A brassinosteroid with protective effects
SD 1008
SD 1008 是一种有效的 JAK 抑制剂。 SD 1008 抑制 STAT3、JAK2 和 Src 的酪氨酰磷酸化。 SD 1008 还降低 STAT3 依赖性荧光素酶活性。 SD 1008 通过直接阻断 JAK-STAT3 信号通路增强紫杉醇诱导的卵巢癌细胞凋亡。
Selonsertib (GS-4997)
An ASK1 inhibitor
Gambogic Acid
A xanthonoid with anticancer activity
ML-291
An activator of apoptosis through UPR
YM155
A small molecule survivin suppressant
D-NMAPPD
A ceramidase inhibitor
Elesclomol (STA-4783)
An apoptosis inducer
Adarotene
An atypical retinoid