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PG 01
PG 01 是一种有效的 CFTR Cl-通道增效剂。
Ivacaftor (VX-770)
A CFTR potentiator
IOWH-032
A modulator of CFTR
PTC124(Ataluren)
Selective inducer of stop codon read-through
Ivacaftor benzenesulfonate
Ivacaftor hydrate
CFTRinh-172
A potent CFTR channel blocker
VX-661
An investigational compound that promotes the maturation of delta F508 CFTR
VX-809
A F508del-CFTR corrector
PPQ-102
A CFTR channel inhibitor
GlyH-101
A reversible CFTR channel blocker
BPO-27 racemate
BPO-27racemate是有效的CFTR抑制剂,IC50值为8nM。
(R)-BPO-27
(R)-BPO-27是有效的CFTR抑制剂,IC50值为4nM。
CFTR corrector 2
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
PTI-428
Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier that increases CFTR expression.