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α-Conotoxin PnIA
A peptide antagonist of α3β2-subunit containing and α7 nAChRs
α-Conotoxin AuIB
A conotoxin and an antagonist of α3β4 subunit-containing nAChRs
GTS 21 dihydrochloride
An agonist of α7-containing nAChRs
RJR 2429 dihydrochloride
An nAChR agonist
AR-R 17779 hydrochloride
AR-R 17779 hydrochloride 是一种有效的、选择性的 nAChR 完全激动剂,对 α7 和 α4β2 亚型的 Kis 分别为 92 和 16000 nM。
EVP-6124 hydrochloride
A partial agonist of α7 subunit-containing nAChRs
TMPH hydrochloride
neuronal nicotinic ACh receptors (nAChRs) antagonist
5-Iodo-A-85380 dihydrochloride
α4β2 and α6β2 nicotinic acetylcholine receptors agonist
PNU-120596
An α7 neuronal nAChR modulator
CCMI
CCMI (AVL-3288) 是一种有效且选择性的 α7 nAChR 阳性变构调节剂,不通过正构位点结合或激活 α7 nAChRs,并导致激动剂诱导的 α7 nAChRs 电流显着正向调节。
Ivermectin
A mixture of ivermectin B1a and ivermectin B1b
Varenicline
Varenicline (CP 526555) 是一种有效的 α4β2 烟碱乙酰胆碱受体 (nAChR) 部分激动剂,EC50 值为 2.3 μM。
LY 2087101
Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
PNU 282987
A potent, selective agonist of α7-containing nAChRs
SIB 1553A hydrochloride
A β4 subunit-selective nAChR agonist