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2-HBA
An indirect inhibitor of Keap1-Nrf2 interactions
Oltipraz
A Nrf2 and CAR activator
NK 252
A Nrf2 activator
Omaveloxolone (RTA-408)
A synthetic triterpenoid that blocks Keap1/Nrf2 signaling
MMF
An active metabolite of dimethyl fumarate
TAT 14
TAT 14 是一种 14 聚体肽,可作为具有抗炎作用的 Nrf2 激活剂。
2-Trifluoromethyl-2'-methoxychalcone
A potent activator of Nrf2
AI-3
Nrf2/Keap1 and Keap1/Cul3 interaction inhibitor
Dimethyl Fumarate
An antioxidant with immunological actions
CDDO-TFEA
A synthetic triterpenoid with potent anticancer and neuroprotective activity
AEM1
An inhibitor of Nrf2-induced gene expression
DL-Sulforaphane N-acetyl-L-cysteine
An anticancer agent
KI696
KI696是一种干扰Keap1/NRF2相互作用的高亲和力探针。
4-Octyl Itaconate
4-Octyl Itaconate 是一种可渗透细胞的衣康酸酯衍生物。
(+)-DHMEQ
(+)-DHMEQ 是抗氧化转录因子 Nrf2 的激活剂。