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5'-Fluoroindirubinoxime
An inhibitor of FLT3 kinase
SKLB4771 (FLT3-IN-1)
SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10?nM.
FLT3-IN-1
FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.
FLT3-IN-1 Succinate
FLT3-IN-1Succinate是有效地FLT3抑制剂,来自专利WO2015056683A1,化合物实例A。
TAK-659
TAK-659 is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
FLT3-IN-2
An inhibitor of FLT3, c-Kit, and c-FMS
Gilteritinib hemifumarate
A FLT3 inhibitor
AZM475271 (M475271)
An inhibitor of c-Src kinase
UNC2025
An orally bioavailable inhibitor of Mer and Flt3
FLT3 Inhibitor III
A potent, highly selective inhibitor of FLT3
MRX-2843 (UNC2371)
A Mer and FLT3 inhibitor
Gilteritinib
Tandutinib (MLN518)
An antagonist of PDGFRβ, FLT3, and c-Kit
TCS 359
A cell-permeable FLT3 inhibitor
BPR1J-097
An FLT3 inhibitor