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TIC10 isomer
TIC10异构体是TIC10的异构体。
ISRIB
ISRIB是PERK信号抑制剂
FR 180204
A potent, cell-permeable inhibitor of ERK1/2
GSK2656157
A PERK inhibitor
XMD8-92
A selective ERK5 inhibitor
Ulixertinib (hydrochloride)
An ERK1/2 inhibitor
ML-191
An antagonist of GPR55
GDC-0994
A selective ERK1/2 inhibitor
XMD17-109
VX-11e
A selective ERK inhibitor
NVP 231
A potent and reversible inhibitor of ceramide kinase
ISRIB (trans-isomer)
An inhibitor of the Integrated Stress Response
SCH772984
A selective inhibitor of ERK1/2
DEL-22379
An inhibitor of ERK dimerization
VRT752271
VRT752271 (BVD-523; VRT752271) 是一种有效的、具有口服活性、高度选择性、ATP 竞争性和可逆的 ERK1/2 激酶共价抑制剂,对 ERK2 的 IC50 <0.3 nM。 VRT752271 (BVD-523; VRT752271) 抑制 A375 黑色素瘤细胞系中的磷酸化 ERK2 (pERK) 和下游激酶 RSK (pRSK)。