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Pomalidomide 4'-PEG5-acid (Pomalidomide-PEG5-CO2H) 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 cereblon 配体和 5 单元 PEG 接头。
Functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand plus a PEG5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC? is a registered trademark of Arvinas Operations, Inc., and is used under license.
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