ONO 2506

An inhibitor of astrocyte activation

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库存: 现货

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数量
10mg

￥1212.00

970.00

- +
25mg

￥1962.00

1570.00

- +
50mg

￥3050.00

2440.00

- +
100mg

￥5400.00

4320.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajci5546
CAS: 185517-21-9
别名: (R)-(-)-2-丙基辛酸,ONO-2506; (R)-2-Propyloctanoic acid
分子式: C11H22O2
分子量: 186.29
纯度: >98%
溶解度: <18.63mg/ml in DMSO; <18.63mg/ml in ethanol
储存: Store at -20°C
库存: 现货

Background

Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].

参考文献:
[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506:? A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.
[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.