Flavin adenine dinucleotide disodium

A flavin dinucleotide

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
100mg

￥675.00

540.00

- +
500mg

￥2700.00

2160.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci8124
CAS: 84366-81-4
别名: 黄素腺嘌呤二核苷酸二钠; FAD disodium salt; FAD-Na2
分子式: C27H31N9Na2O15P2
分子量: 829.51
纯度: >98%
溶解度: ≥ 207.5mg/mL in Water
储存: 4°C, protect from light
库存: 现货

Background

Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

Poly(Flavin Adenine Dinucleotide, FAD) characterized by an additional polymer-type redox reaction is a highly effective electrocatalyst for NADH oxidation: operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) is characterized by the electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes are characterized by the dramatically improved stability and, is the most advantageous NADH transducers for analytical chemistry[2].

With flavin adenine dinucleotide (2 mg/kg), the chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT) is significantly cancelled. Flavin Adenine Dinucleotide cancels the effect of CPZ on canine heart mitochondria. After injection of Flavin Adenine Dinucleotide, the dogs show a transient hypotension within 10 min, then their blood pressures recover to the initial level. Flavin Adenine Dinucleotide also prevents mitochondrial dysfunction induced by chlorpromazine[1].

参考文献:
[1]. Sugiyama S, et al. Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. Jpn Heart J. 1979 Sep;20(5):657-65.
[2]. Karyakin AA, et al. Electropolymerized flavin adenine dinucleotide as an advanced NADH transducer. Anal Chem. 2004 Apr 1;76(7):2004-9.