Avermectin B1b

An insecticide and anthelmintic

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500ug

￥4500.00

3600.00

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2.5mg

￥16712.00

13370.00

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货号: ajci16174
CAS: 65195-56-4
别名: 阿维菌素B1b,Abamectin B1b, Antibiotic C 076B1b
分子式: C47H70O14
分子量: 859.05
纯度: >98%
溶解度: Soluble in ethanol, or in methanol, or in DMSO, or in DMF
储存: Store at -20°C
库存: 现货

Background

Avermectins are insecticides and anthelmintics first isolated from broths fermented by S. avermitilis.[1] They potentiate glutamate- and GABA-gated chloride channel opening in nematodes.[2],[3] Avermectin B1b is a minor component of avermectin broth.[2] Avermectins, including avermectin B1b, are used broadly against nematodes, ticks, flies, and ants.[2]

Reference:
[1]. Egerton, J.R., Ostlind, D.A., Blair, L.S., et al. Avermectins, new family of potent anthelmintic agents: Efficacy of the B1a component. Antimicrobial Agents and Chemotherapy 15(3), 372-378 (1979).
[2]. Duke, S.O., Cantrell, C.L., Meepagala, K.M., et al. Natural toxins for use in pest management. Toxins (Basel) 2(8), 1943-1962 (2010).
[3]. Arena, J.P., Liu, K.K., Paress, P.S., et al. The mechanism of action of avermectins in Caenorhabditis elegans: Correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity. Journal of Parasitology 81(2), 286-294 (1995).