Chlorhexidine digluconate

氯己定二葡萄糖酸盐是一种对多种革兰氏阴性和革兰氏阳性微生物有效的防腐剂。

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50mg

￥625.00

500.00

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Background

Chlorhexidine digluconate is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.Target: AntibacterialChlorhexidine digluconate is a chemical antiseptic. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action, the mechanism of action being membrane disruption, not ATPase inactivation as previously thought. It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. Chlorhexidine digluconate is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions [1, 2].

参考文献:
[1]. Jenkins, S., M. Addy, and W. Wade, The mechanism of action of chlorhexidine. A study of plaque growth on enamel inserts in vivo. J Clin Periodontol, 1988. 15(7): p. 415-24.
[2]. Maki, D.G., M. Ringer, and C.J. Alvarado, Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet, 1991. 338(8763): p. 339-43.