Nafamostat hydrochloride

Nafamostat hydrochloride 是一种合成丝氨酸蛋白酶抑制剂，是一种抗凝剂。

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库存: 现货

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数量
10mg

￥450.00

360.00

- +
50mg

￥1300.00

1040.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Nafamostat hydrochloride, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat hydrochloride supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis[1][2][3].

参考文献:
[1]. Ikehara S, et al. Effect of FUT-175, a new synthetic protease inhibitor, on the development of lupus nephritis in (NZB x NZW) F1 mice. Immunology. 1985 Aug;55(4):595-600.
[2]. Homma S, et al. Nafamostat mesilate, a serine protease inhibitor, suppresses interferon-gamma-induced up-regulation of programmed cell death ligand 1 in human cancer cells. Int Immunopharmacol. 2018 Jan;54:39-45.
[3]. Pak K, et al. Effectiveness of FUT-175, protease inhibitor, as an anticoagulant to hemodialysis. Hinyokika Kiyo. 1988 Jun;34(6):1077-81.