Moxidectin

A macrocyclic lactone endectocide

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库存: 现货

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1mg

￥1325.00

1060.00

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货号: ajci18408
CAS: 113507-06-5
别名: 莫昔克丁; CL301423
分子式: C37H53NO8
分子量: 639.82
纯度: >98%
溶解度: ≥ 129.4 mg/mL in DMSO, ≥ 128 mg/mL in EtOH, ≥ 3.27 mg/mL in Water with ultrasonic and warming
储存: Store at -20°C
库存: 现货

Background

Moxidectin(ProHeart 6; CL301423; Cydectin) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.IC50 value:Target: Anti-parasiticMoxidectin is a semisynthetic derivative of nemadectin, which is produced by fermentation by Streptomyces cyano-griseus. Moxidectin treats and controls some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite. Studies of moxidectin show the side effects vary by animal and may be affected by the product’s formulation, application method and dosage.

参考文献:
[1]. Moxidectin, From Wikipedia