Carebastine

An active metabolite of ebastine and a histamine H1 receptor antagonist

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库存: 现货

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促销价

数量
5mg

￥900.00

720.00

- +
10mg

￥1412.00

1130.00

- +
25mg

￥1975.00

1580.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajci20638
CAS: 90729-42-3
别名: 卡依巴司丁
分子式: C32H37NO4
分子量: 499.6
纯度: >98%
溶解度: DMF: 25 mg/ml,DMSO: 2 mg/ml,Ethanol: 2 mg/ml
储存: Store at -20°C
库存: 现货

Background

Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].

参考文献:
[1]. De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34(4):958-66.
[2]. Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33(6):785-7.