Stachyose (hydrate)

An oligosaccharide and prebiotic

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库存: 现货

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数量
250mg

￥900.00

720.00

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500mg

￥1725.00

1380.00

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1g

￥3250.00

2600.00

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5g

￥10775.00

8620.00

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货号: ajci20732
CAS: 54261-98-2
别名: 水苏糖
分子式: C24H42O21·XH2O
分子量: 666.6
纯度: >98%
溶解度: DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存: -20°C
库存: 现货

Background

Stachyose is an oligosaccharide and prebiotic.^1,2,3 In vivo, stachyose (1 g/kg per day) reduces the number of colonic lesions and serum TNF-α, IL-6, IL-10, and IL-17a levels, as well as increases gut levels of Akkermansia and the probiotic Lactobacillus, in a rat model of colitis induced by dextran sulfate .¹ It decreases serum LPS, IL-6, and TNF-α levels and enriches Phascolarctobacterium, Bilophila, Oscillospira, and Turicibacter in the gut microbiota in a rat model of diabetes induced by high-fat diet and streptozotocin .² Stachyose also enhances berberine-induced blood glucose control and improvements in insulin resistance, as well as decreases the fecal concentration of short-chain fatty acids, in the KKAγ mouse model of type 2 diabetes.³

1.He, L., Zhang, F., Jian, Z., et al.Stachyose modulates gut microbiota and alleviates dextran sulfate sodium-induced acute colitis in miceSaudi J. Gastroenterol.26(3)153-159(2020) 2.Liu, G., Bei, J., Liang, L., et al.Stachyose improves inflammation through modulating gut microbiota of high-fat diet/streptozotocin-induced type 2 diabetes in ratsMol. Nutr. Food Res.62(6)e1700954(2018) 3.Cao, H., Li, C., Lei, L., et al.Stachyose improves the effects of berberine on glucose metabolism by regulating intestinal microbiota and short-chain fatty acids in spontaneous type 2 diabetic KKAy miceFront. Pharmacol.11578943(2020)