Prostaglandin H2

2-series PGs and thromboxane precursor

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库存: 现货

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50ug

￥1100.00

880.00

- +
100ug

￥1937.00

1550.00

- +
500ug

￥10037.00

8030.00

- +
1mg

￥17862.00

14290.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor.[1]? PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), [2]? and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100 ng/ml.

Reference：
[1]. Hamberg, M., Svensson, J., Wakabayashi, T., et al. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America 71, 345-349 (1974).
[2]. Samuelsson, B., Goldyne, M., Granstr?m, E., et al. Prostaglandins and thromboxanes. Annu. Rev. Biochem. 47, 997-1029 (1978).