Elinogrel

A reversible P2Y12 antagonist

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库存: 现货

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1mg

￥562.00

450.00

- +
5mg

￥1787.00

1430.00

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货号: ajci21186
CAS: 936500-94-6
别名: 5-氯-N-[[[4-[6-氟-1,4-二氢-7-(甲基氨基)-2,4-二氧代-3(2H)-喹唑啉基]苯基]氨基]羰基]-2-噻吩磺酰胺,PRT060128
分子式: C20H15ClFN5O5S2
分子量: 523.9
纯度: >98%
溶解度: DMSO: 100 mM
储存: Store at -20°C
库存: 现货

Background

Elinogrel (PRT060128) is a potent, direct acting, competitive, and reversible platelet P2Y12 antagonist (IC50=20 nM). It is orally and intravenously available and has potent antiplatelet effects[1].

参考文献:
[1]. Angiolillo DJ, et al. Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudyfrom the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patients (INNOVATE-PCI) trial. Circ Cardiovasc Interv. 2012 Jun;5(3):347-56.
[2]. Jacobson KA, et al. Pharmacochemistry of the platelet purinergic receptors. Purinergic Signal. 2011 Sep;7(3):305-24.