Propofol β-D-Glucuronide

A metabolite of propofol

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库存: 现货

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500ug

￥537.00

430.00

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1mg

￥962.00

770.00

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5mg

￥3550.00

2840.00

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10mg

￥6687.00

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货号: ajci21380
CAS: 114991-26-3
别名: 2,6-二异丙基Β-D-吡喃葡萄糖酸
分子式: C18H26O7
分子量: 354.4
纯度: >98%
溶解度: 30mg/mL in DMSO, 30mg/mL in DMF, 30mg/mL in Ethanol
储存: Store at -20°C
库存: 现货

Background

Propofol β-D-glucuronide is a metabolite of propofol sulfate , a short-acting anesthetic agent. [1] [2] The metabolite is generated through the glucuronidation of propofol by uridine diphosphate glucuronosyltransferases. Propofol metabolism appears to occur more rapidly in women than men. [1]

Reference:
[1]. Choong, E., Loryan, I., Lindqvist, M., et al. Sex difference in formation of propofol metabolites: A replication stud. Basic Clin.Pharmacol.Toxicol. 113(2), 126-131 (2013).
[2]. S?rensen, L.K., and Hasselstr?m, J.B. Simultaneous determination of propofol and its glucuronide in whole blood by liquid chromatography-electrospray tandem mass spectrometry and the influence of sample storage conditions on the reliability of the test results. J.Pharm.Biomed.Anal. 109, (2015).