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  • (+)-Rugulosin
(+)-Rugulosin的可视化放大

(+)-Rugulosin

A mycotoxin

原价
¥1750-3175
价格
1400-2540
(+)-Rugulosin的二维码

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  • 库存: 现货
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  • 货号: ajci21740
  • CAS: 23537-16-8
  • 别名: 细皱青霉素+FORM,(+)-Rugulosin
  • 分子式: C30H22O10
  • 分子量: 542.5
  • 纯度: >98%
  • 溶解度: DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
  • 储存: Store at -20°C; protect from light
  • 库存: 现货

Background

(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 uM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 uM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 uM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 ug/ml, respectively).

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