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  • Leukotriene F4
Leukotriene F4的可视化放大

Leukotriene F4

A CysLT produced in vitro from LTE4

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Leukotriene F4的二维码
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  • 25ug
    ¥2262.00
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  • 货号: ajci21932
  • CAS: 83851-42-7
  • 别名: 白三烯,LTF4
  • 分子式: C28H44N2O8S
  • 分子量: 568.7
  • 纯度: >98%
  • 溶解度: >50 mg/ml (per Ramki Iyer) in DMSO, >50 mg/ml (per Ramki Iyer) in DMF, >50 mg/ml (per Ramki Iyer) in Ethanol
  • 储存: Store at -80°C
  • 库存: 现货

Background

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle. [1]? The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4. [1] [2]


Reference:
[1]. Bernstrom, K., and Hammarstr?m, S. A novel leukotriene formed by transpeptidation of leukotriene E4. Biochemical and Biophysical Research Communications 109, 800-804 (1982).
[2]. Lord, A., Charleson, S., and Letts, L.G. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. Prostaglandins 29, 651-660 (1985).

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