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  • tetranor-PGJM
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tetranor-PGJM

An expected urinary metabolite of PGD2

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  • 货号: ajci22084
  • CAS: 1352751-83-7
  • 别名: tetranorPGJ Metabolite
  • 分子式: C16H22O6
  • 分子量: 310.3
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in human and mouse and, as such, is used as a biomarker of PGD2 biosynthesis. tetranor-PGJM is a potential PGD2 metabolite, formed by the elimination of the C-9 hydroxyl group. This compound may serve as a useful control in the analysis of PGD2 biosynthesis.

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