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  • Ebelactone A
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Ebelactone A

An esterase inhibitor

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Ebelactone A的二维码
  • 库存: 现货
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  • 包装
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  • 500ug
    ¥1012.00
    810.00
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  • 1mg
    ¥1612.00
    1290.00
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  • 货号: ajci64796
  • CAS: 76808-16-7
  • 别名: (-)-Ebelactone A, NSC 335650
  • 分子式: C20H34O4
  • 分子量: 338.5
  • 纯度: >98%
  • 溶解度: DMF: 25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 25 mg/ml,Ethanol: 20 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Ebelactone A is a β-lactone enzyme inhibitor that was first isolated from a cultured strain of soil actinomycetes. It can inhibit esterases, lipases, and N-formylmethionine aminopeptidases (IC50s = 0.056, 0.003, and 0.08 µg/ml, respectively) found on cell surfaces, which has been shown to stimulate host defense in immune cells. Ebelactone A is also reported to inhibit cutinases produced by fungal pathogens, thus demonstrating a plant-protective function.

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