Used in neoglycoprotein preparation
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α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.[1]? Neoglycoproteins are used to identify the presence and sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells and to study membrane lectin-mediated endocytosis.
参考文献
[1]. Monsigny, M., Roche, A.C., and Midoux, P. Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting. Biol.Cell 51(2), 187-196 (1984).
LX1606 Hippurate (Telotristat etiprate)
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