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  • Prostaglandin A3
Prostaglandin A3的可视化放大

Prostaglandin A3

Exhibits good affinity for canine EP2 and EP4 receptors

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Prostaglandin A3的二维码
  • 库存: 现货
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  • 包装
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  • 25ug
    ￥1625.00
    1300.00
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  • 50ug
    ￥2687.00
    2150.00
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  • 100ug
    ￥4925.00
    3940.00
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已选 0 种 0 瓶
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使用我司产品发表的文章

  • 货号: ajci65772
  • CAS: 36614-31-0
  • 别名: 胃蛋白酶A
  • 分子式: C20H28O4
  • 分子量: 332.4
  • 纯度: >98%
  • 溶解度: DMF: >75 mg/ml (from PGA1),DMSO: >50 mg/ml (from PGA1),Ethanol: >100 mg/ml (from PGA1),PBS pH 7.2: >2.4 mg/ml (from PGA1)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively, in a radioligand binding assay. PGA3 has weak affinity for human PPARγ, with a Ki value of 188 µM.

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