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  • 17-phenyl trinor Prostaglandin F2α
17-phenyl trinor Prostaglandin F2α的可视化放大

17-phenyl trinor Prostaglandin F2α

Potent FP receptor agonist

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17-phenyl trinor Prostaglandin F2α的二维码
  • 库存: 现货
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  • 1mg
    ¥950.00
    760.00
    - +
  • 5mg
    ¥4237.00
    3390.00
    - +
  • 10mg
    ¥7550.00
    6040.00
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  • 25mg
    ¥16375.00
    13100.00
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  • 货号: ajci66222
  • CAS: 38344-08-0
  • 别名: 贝美前列素C1酸
  • 分子式: C23H32O5
  • 分子量: 388.5
  • 纯度: >98%
  • 溶解度: DMF: >100 mg/ml (from Fluprostenol),DMSO: >100 mg/ml (from Fluprostenol),Ethanol: >100 mg/ml (from Fluprostenol),PBS pH 7.2: >800 μ g/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. At the rat recombinant FP receptor expressed in CHO cells bimatoprost inhibits PGF2α binding with a Ki of 1.1 nM. The isopropyl ester of 17-phenyl trinor PGF2α ethyl amide is slightly better than PGF2α isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation.

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