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  • 15(R)-15-methyl Prostaglandin F2α
15(R)-15-methyl Prostaglandin F2α的可视化放大

15(R)-15-methyl Prostaglandin F2α

A prodrug PGF agonist that is converted to a luteolytic agent

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15(R)-15-methyl Prostaglandin F2α的二维码
  • 库存: 现货
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  • 包装
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  • 500ug
    ￥1212.00
    970.00
    - +
  • 1mg
    ￥2312.00
    1850.00
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  • 货号: ajci67122
  • CAS: 35864-81-4
  • 别名: 15(R)15methyl PGF2α
  • 分子式: C21H36O5
  • 分子量: 368.5
  • 纯度: >98%
  • 溶解度: 10 mM Na2CO3: >6.5 mg/ml (from PGF2a),DMF: >100 mg/ml (from PGF2a),DMSO: >100 mg/ml (from PGF2a),Ethanol: >100 mg/ml (from PGF2a),PBS pH 7.2: >10 mg/ml (from PGF2a)
  • 储存: Store at -20°C
  • 库存: 现货

Background

15(R)-15-methyl PGF2α is a metabolically stable analog of PGF2α. 15(R)-15-methyl PGF2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-methyl PGF2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.

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