Artemisinic Acid

A sesquiterpene

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库存: 现货

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数量
5mg

￥462.00

370.00

- +
10mg

￥675.00

540.00

- +
25mg

￥1612.00

1290.00

- +
50mg

￥2912.00

2330.00

- +
100mg

￥4400.00

3520.00

- +

已选 0 种 0 瓶

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货号: ajci67462
CAS: 80286-58-4
别名: 青蒿酸; Qing Hao acid; Artemisinic acid; Arteannuic acid
分子式: C15H22O2
分子量: 234.3
纯度: >98%
溶解度: DMF: 20 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 10 mg/ml,Ethanol: 16 mg/ml
储存: Store at -20°C, stored under nitrogen
库存: 现货

Background

Artemisinic acid is a sesquiterpene that has been isolated from A. annua. It has been used in the synthesis of the antimalarial agent artemisinin . Artemisinic acid (50-400 µM) decreases triglyceride levels and glycerol-3-phosphate dehydrogenase (GPDH) activity in human adipose tissue-derived mesenchymal stem cells (hAMSCs) in a dose-dependent manner and inhibits adipocyte differentiation when used at a concentration of 200 µM. It reduces mRNA expression and protein levels of C/EBPα, C/EBPδ, and PPARγ as well as the ratio of phosphorylated JNK to JNK in hAMSCs. Artemisinic acid also decreases C/EBPα and HMG-CoA reductase mRNA expression and inhibits cholesterol synthesis and melanogenesis in human epidermal melanocytes.