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  • 16,16-dimethyl Prostaglandin A2
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16,16-dimethyl Prostaglandin A2

A metabolism resistant analog of PGA2

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16,16-dimethyl Prostaglandin A2的二维码
  • 库存: 现货
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    数量
  • 1mg
    ¥1525.00
    1220.00
    - +
  • 5mg
    ¥6837.00
    5470.00
    - +
  • 10mg
    ¥12037.00
    9630.00
    - +
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  • 货号: ajci68126
  • CAS: 41691-92-3
  • 别名: 16,16dimethyl PGA2
  • 分子式: C22H34O4
  • 分子量: 362.5
  • 纯度: >98%
  • 溶解度: DMF: >75 mg/ml (from PGA1),DMSO: >50 mg/ml (from PGA1),Ethanol: >100 mg/ml (from PGA1),PBS pH 7.2: >2.4 mg/ml (from PGA1)
  • 储存: Store at -20°C
  • 库存: 现货

Background

16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 µg/ml. Daily infusion of 10 µg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time.

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