安捷凯生物医药
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  • Compound C108
Compound C108的可视化放大

Compound C108

A G3BP2 inhibitor

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Compound C108的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥175.00
    140.00
    - +
  • 1mg
    ￥350.00
    280.00
    - +
  • 5mg
    ￥1525.00
    1220.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci70854
  • CAS: 15533-09-2
  • 别名:
  • 分子式: C15H14N2O3
  • 分子量: 270.3
  • 纯度: >98%
  • 溶解度: DMF: 1 mg/ml,DMF:PBS(pH 7.2)(1:6): 0.14 mg/ml,DMSO: 1 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. In a mouse xenograft model of breast cancer, compound C108 (1 µM for 24 hours) reduces the proportion of tumor-initiating cells approximately 10-fold compared with untreated cells. In MDA-MB-453 cells, and in the patient-derived xenograft cell line MAXF 401, it diminishes mammosphere formation.

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