DEPMPO

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50mg

￥1745.00

1396.00

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250mg

￥7161.00

5728.00

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500mg

￥12972.00

10377.00

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DEPMPO is a phosphorylated derivative of the widely used DMPO spin trap.

货号：ajci71062
CAS：157230-67-6
分子式：C9H18NO4P
分子量：235.2
纯度：98%
存储：Store at -80°C
库存：现货

Background:

DEPMPO is a phosphorylated derivative of the widely used DMPO spin trap. It has been reported to produce spin adducts with increased stability particularly for the adduct of superoxide. [1] [2] [3] DEPMPO displays a detectable spin adduct signal at a concentration as low as 1 mM, as compared to 5 mM for DMPO.[3] A signi?cant advantage of using DEPMPO in trapping superoxide radical is that the decomposition of DEPMPO/O2?- does not produce the OH? adduct, which can be a drawback when using DMPO. [2][3]

参考文献：

[1]. Khan, N., Wilmont, C.M., Rosen, G.M., et al. Spin traps: In vitro toxicity and stability of radical adducts. Free Radical Biology & Medicine 34(11), 1473-1481 (2003).

[2]. Anzai, K., Aikawa, T., Furukawa, Y., et al. ESR measurement of rapid penetration of DMPO and DEPMPO spin traps through lipid bilayer membranes. Archives of Biochemistry and Biophysics 415, 251-256 (2003).

[3]. Liu, K.J., Miyake, M., Panz, T., et al. Evaluation of DEPMPO as a spin trapping agent in biological systems. Free Radical Biology & Medicine 26, 714-721 (1999).