A natural H2S donor
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Diallyl disulfide (DADS) is an organosulfur compound derived from allicin, a natural compound found in garlic and related plants. DADS has diverse physiological effects, many that are cardio- and neuro-protective. These effects are due, at least in part because DADS is converted, in the presence of thiols, to the gaseous mediator hydrogen sulfide (H2S). Thus, DADS serves as a thiol-dependent H2S donor in biological systems.
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