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  • EGA
EGA的可视化放大

EGA

An inhibitor of endosomal trafficking

原价
¥512-5762
价格
410-4610
EGA的二维码

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  • 货号: ajci71418
  • CAS: 415687-81-9
  • 别名:
  • 分子式: C16H16BrN3O
  • 分子量: 346.2
  • 纯度: >98%
  • 溶解度: DMSO: 5 mg/ml
  • 储存: Store at -20°C,protect from light
  • 库存: 现货

Background

EGA is an inhibitor of endosomal trafficking. It increases accumulation of fluorescently labeled EGF in early endosomes in HeLa cells when used at a concentration of 20 μM. EGA inhibits cell death induced by anthrax lethal toxin in RAW264.7 cells (IC50 = 1.7 μM) as well as by additional acid-dependent bacterial toxins, including diphtheria toxin, P. aeruginosa ExoA, and H. ducreyi cytolethal distending toxin (Hd-CDT), in various cell types. It also inhibits infection of Vero and HeLa cells by the low pH-dependent lymphocytic choriomeningitis (LCMV; Armstrong strain) and influenza A/WSN/33 viruses, respectively.

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