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  • Galactosylsphingosine (d18:1)
Galactosylsphingosine (d18:1)的可视化放大

Galactosylsphingosine (d18:1)

A bioactive sphingolipid

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Galactosylsphingosine (d18:1)的二维码
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  • 1mg
    ¥937.00
    750.00
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  • 5mg
    ¥3912.00
    3130.00
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  • 10mg
    ¥6000.00
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  • 货号: ajci71688
  • CAS: 2238-90-6
  • 别名: 神经鞘氨醇半乳糖苷,Galactosylsphingosine
  • 分子式: C24H47NO7
  • 分子量: 461.6
  • 纯度: >98%
  • 溶解度: Ethanol: >1 mg/ml; PBS (pH 7.2): >1 mg/ml
  • 储存: Store at -20°C, protect from light
  • 库存: 现货

Background

Galactosylsphingosine is a galactoside of sphingosine and a constituent of cerebrosides. The lysosomal enzyme β-galactosylceramidase is responsible for cleaving the glycosydic linkage of galactosylceramide and galactosylsphingosine. Accumulation of galactosylsphingosine during β-galactosylceramidase deficiency, as seen with Krabbe disease, is cytotoxic and preferentially affects oligodendrocytes, leading to progressive demyelination and infiltration of activated macrophages into the brain.

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