Ganglioside GQ1b Mixture (sodium salt)

A mixture of ganglioside GQ1b

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500ug

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货号: ajci71710
CAS: 68652-37-9
别名: 神经节苷脂GQ1B四钠盐
分子式: C106H178N6O55?4Na (for Sphingosine C18:1)
分子量: 2508.5
纯度: >98%
溶解度: Chloroform:Methanol (2:1): Soluble,Water: Soluble
储存: Store at -20°C
库存: 现货

Background

Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes through phosphoinositide turnover. Ganglioside GQ1b mixture contains ganglioside GQ1b molecular species with C18:1 and C20:1 sphingoid backbones.