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  • I-SAP
I-SAP的可视化放大

I-SAP

A high-affinity TP receptor antagonist

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I-SAP的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 100ug
    ¥1212.00
    970.00
    - +
  • 500ug
    ¥5450.00
    4360.00
    - +
  • 1mg
    ¥9687.00
    7750.00
    - +
已选 0 0
金额: ¥0.00
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  • 货号: ajci72062
  • CAS: 133538-58-6
  • 别名: Iodophenyl sulfonyl amino pinane Thromboxane A2, Iodophenyl sulfonyl amino pinane TXA2
  • 分子式: C22H30INO4S
  • 分子量: 531.4
  • 纯度: >98%
  • 溶解度: DMF: >50 mg/ml (from Pinane TXA2),DMSO: >25 mg/ml (from Pinane TXA2),Ethanol: >100 mg/ml (from Pinane TXA2),PBS pH 7.2: >100 μ g/ml (from Pinane TXA2)
  • 储存: Store at -20°C
  • 库存: 现货

Background

I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.

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