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  • K252b
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K252b

A cell-impermeable kinase inhibitor

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K252b的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥3312.00
    2650.00
    - +
  • 1mg
    ￥6237.00
    4990.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci72228
  • CAS: 99570-78-2
  • 别名:
  • 分子式: C26H19N3O5
  • 分子量: 453.5
  • 纯度: >98%
  • 溶解度: Methanol: 2 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

K252b is an indolocarbazole isolated from the actinomycete Nocardiopsis, first described as an inhibitor of protein kinase C. However, as this compound does not freely pass through the cell membrane, it is used to inhibit extracellular kinases (ectokinases) of cells in culture. K252b inhibits receptor-mediated degranulation from basophil-like RBL-2H3 cells (IC50 = 0.5 μg/ml) and human basophils. This extracellular inhibitor is also used in comparison studies with the closely related, cell-permeable inhibitor K252a, particularly in studies of neuronal differentiation.

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